Introduction: Injury is common incident in most of the sports and games. There are many reasons for the factors incident of injuries, the psychological aspect can be considered as one of them. Method: The aim of present study was to examine the relationship between psychological skills and severity of injuries in football players of Tehran premier league. 108 players of Iran premier league participated in the study. Research data was collected by injury report form and Ottawa mental skills assessment tool-3. Pearson correlation test at significant level of 95% were used for analyzing the data. Results: 90.7 % of them resulted in 1-3 days missing of match or training and there is inverse and significant relationship between psychological skills and its subdivisions (P=0/0001) and severity of sport injuries in football players. Conclusion: The findings of present study show that having high levels of psychological skills helps premier league players to handle stressful situations in sports through enhancing self-confidence and other psychological factors confronting harmful psychological factors such as stress and anxiety and lead to decrease in injury severity.